Characterization of Potential Melanoma Predisposition Genes in High-Risk Brazilian Patients

Characterization of Potential Melanoma Predisposition Genes in High-Risk Brazilian Patients

Increased genetic risk for melanoma can occur in the context of germline pathogenic variants in high-penetrance genes, such as <i>CDKN2A</i> and <i>CDK4</i>, risk variants in low- to moderate-penetrance genes (<i>MC1R</i> and <i>MITF</i>), and possibly...

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Bibliographic Details
Main Authors: Bianca Costa Soares de Sá, Luciana Facure Moredo, Giovana Tardin Torrezan, Felipe Fidalgo, Érica Sara Souza de Araújo, Maria Nirvana Formiga, João Pereira Duprat, Dirce Maria Carraro
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:International Journal of Molecular Sciences
Subjects:
familial melanoma
melanoma predisposition
melanoma susceptibility
germline pathogenic variants
multiple primary neoplasms
Online Access:https://www.mdpi.com/1422-0067/24/21/15830

Internet

https://www.mdpi.com/1422-0067/24/21/15830

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