Phenalen-1-one-Mediated Antimicrobial Photodynamic Therapy: Antimicrobial Efficacy in a Periodontal Biofilm Model and Flow Cytometric Evaluation of Cytoplasmic Membrane Damage

Phenalen-1-one-Mediated Antimicrobial Photodynamic Therapy: Antimicrobial Efficacy in a Periodontal Biofilm Model and Flow Cytometric Evaluation of Cytoplasmic Membrane Damage

In light of increasing resistance toward conventional antibiotics and antiseptics, antimicrobial photodynamic therapy (aPDT) may be a valuable alternative, especially for use in dentistry. In this regard, photosensitizers (PS) based on a phenalen-1-one structure seem to be especially favorable due t...

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Bibliographic Details
Main Authors: Fabian Cieplik, Viktoria-Sophia Steinwachs, Denise Muehler, Karl-Anton Hiller, Thomas Thurnheer, Georgios N. Belibasakis, Wolfgang Buchalla, Tim Maisch
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Microbiology
Subjects:
biofilm
periodontal
photodynamic
phenalen-1-one
chlorhexidine
flow cytometry
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2018.00688/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2018.00688/full

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