Klotho relieves inflammation and exerts a cardioprotective effect during renal ischemia/reperfusion-induced cardiorenal syndrome

Klotho relieves inflammation and exerts a cardioprotective effect during renal ischemia/reperfusion-induced cardiorenal syndrome

Background: Renal ischemia and reperfusion injury (IRI) is the main cause of acute kidney injury (AKI). AKI induces the development of cardiac hypertrophy (CH) during cardiorenal syndrome (CRS), and cardiomyocyte calcium mishandling though systemic inflammation after 8 days of renal IRI. Klotho has...

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Bibliographic Details
Main Authors: Carolina Victoria Cruz Junho, Laura González-Lafuente, Raquel Silva Neres-Santos, José Alberto Navarro-García, Elena Rodríguez-Sánchez, Gema Ruiz-Hurtado, Marcela Sorelli Carneiro-Ramos
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Cardiorenal syndrome
Cardiomyocyte
Contractile
Acute kidney injury
Renal ischemia and reperfusion
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222009040

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http://www.sciencedirect.com/science/article/pii/S0753332222009040

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