Decline in cognitively complex everyday activities accelerates along the Alzheimer’s disease continuum

Decline in cognitively complex everyday activities accelerates along the Alzheimer’s disease continuum

Abstract Background Impairment in daily functioning is a clinical hallmark of dementia. Difficulties with “instrumental activities of daily living” (IADL) seem to increase gradually over the course of Alzheimer’s disease (AD), before dementia onset. However, it is currently not well established how...

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Bibliographic Details
Main Authors: Mark A. Dubbelman, Roos J. Jutten, Sarah E. Tomaszewski Farias, Rebecca E. Amariglio, Rachel F. Buckley, Pieter Jelle Visser, Dorene M. Rentz, Keith A. Johnson, Michael J. Properzi, Aaron Schultz, Nancy Donovan, Jennifer R. Gatchell, Charlotte E. Teunissen, Bart N. M. Van Berckel, Wiesje M. Van der Flier, Reisa A. Sperling, Kathryn V. Papp, Philip Scheltens, Gad A. Marshall, Sietske A. M. Sikkes, for the Alzheimer Disease Neuroimaging Initiative, National Alzheimer’s Coordinating Center, the Harvard Aging Brain Study, the Alzheimer Dementia Cohort
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Alzheimer’s Research & Therapy
Subjects:
Alzheimer’s disease
functional impairment
instrumental activities of daily living
clinical stages
Online Access:http://link.springer.com/article/10.1186/s13195-020-00706-2

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http://link.springer.com/article/10.1186/s13195-020-00706-2

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