Delayed Double Treatment with Adult-Sourced Adipose-Derived Mesenchymal Stem Cells Increases Striatal Medium-Spiny Neuronal Number, Decreases Striatal Microglial Number, and Has No Subventricular Proliferative Effect, after Acute Neonatal Hypoxia-Ischemia in Male Rats

Delayed Double Treatment with Adult-Sourced Adipose-Derived Mesenchymal Stem Cells Increases Striatal Medium-Spiny Neuronal Number, Decreases Striatal Microglial Number, and Has No Subventricular Proliferative Effect, after Acute Neonatal Hypoxia-Ischemia in Male Rats

Perinatal hypoxia-ischemia (HI) is a major cause of striatal injury. Delayed post-treatment with adult-sourced bone marrow-derived mesenchymal stem cells (BMSCs) increased the absolute number of striatal medium-spiny neurons (MSNs) following perinatal HI-induced brain injury. Yet extraction of BMSCs...

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Bibliographic Details
Main Authors: Haylee K. Basham, Benjamin E. Aghoghovwia, Panagiotis Papaioannou, Steve Seo, Dorothy E. Oorschot
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
adipose-derived mesenchymal stem cells
adult mesenchymal stem cells
location of extrinsic stem cells in brain
striatal medium-spiny projection neurons
striatal microglia
subventricular zone
Online Access:https://www.mdpi.com/1422-0067/22/15/7862

Internet

https://www.mdpi.com/1422-0067/22/15/7862

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