Homologation of aryl ketones to long-chain ketones and aldehydes via C–C bond cleavage

Summary: Transition metal-catalyzed C–C bond cleavage is a powerful tool for the reconstruction of a molecular skeleton. We report herein the multi-carbon homologation of aryl ketones to long-chain ketones and aldehydes via ligand-promoted Ar−C(O) bond cleavage and subsequent cross coupling with alk...

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Bibliographic Details
Main Authors: Xing Wang, Ling-Jun Li, Zhen-Yu Wang, Hui Xu, Hui-Xiong Dai
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222007763