DR*W201/P65 tetramer visualization of epitope-specific CD4 T-cell during M. tuberculosis infection and its resting memory pool after BCG vaccination.

In vivo kinetics and frequencies of epitope-specific CD4 T cells in lymphoid compartments during M. tuberculosis infection and their resting memory pool after BCG vaccination remain unknown.Macaque DR*W201 tetramer loaded with Ag85B peptide 65 was developed to directly measure epitope-specific CD4 T...

Full description

Bibliographic Details
Main Authors: Huiyong Wei, Richard Wang, Zhuqing Yuan, Crystal Y Chen, Dan Huang, Lisa Halliday, Weihua Zhong, Gucheng Zeng, Yun Shen, Ling Shen, Yunqi Wang, Zheng W Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2731856?pdf=render