The protective effect of inflammatory monocytes during systemic C. albicans infection is dependent on collaboration between C-type lectin-like receptors.

The protective effect of inflammatory monocytes during systemic C. albicans infection is dependent on collaboration between C-type lectin-like receptors.

Invasive candidiasis, mainly caused by Candida albicans, is a serious healthcare problem with high mortality rates, particularly in immunocompromised patients. Innate immune cells express pathogen recognition receptors (PRRs) including C-type lectin-like receptors (CLRs) that bind C. albicans to ini...

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Bibliographic Details
Main Authors: Aiysha Thompson, Luke C Davies, Chia-Te Liao, Diogo M da Fonseca, James S Griffiths, Robert Andrews, Adam V Jones, Mathew Clement, Gordon D Brown, Ian R Humphreys, Philip R Taylor, Selinda J Orr
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-06-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007850

Internet

https://doi.org/10.1371/journal.ppat.1007850

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