Experimental basis for the putative role of GluR6/kainate glutamate receptor subunit in Huntington's disease natural history

Age of onset of Huntington's disease (HD) statistically correlates with the length of expanded CAG repeats in the IT15 gene. However, other factors such as polymorphism in the 3′ untranslated region of the GluR6 kainate receptor gene subunit may contribute to variability in the age at onset. To...

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Bibliographic Details
Main Authors: Elsa Diguet, Pierre-Olivier Fernagut, Elisabeth Normand, Laurie Centelles, Christophe Mulle, François Tison
Format: Article
Language:English
Published: Elsevier 2004-04-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996103002869