Targeting the T-type calcium channel Cav3.2 in GABAergic arcuate nucleus neurons to treat obesity

Targeting the T-type calcium channel Cav3.2 in GABAergic arcuate nucleus neurons to treat obesity

Objective: Cav3.2, a T-type low voltage-activated calcium channel widely expressed throughout the central nervous system, plays a vital role in neuronal excitability and various physiological functions. However, the effects of Cav3.2 on energy homeostasis remain unclear. Here, we examined the role o...

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Bibliographic Details
Main Authors: Bing Feng, Jerney Harms, Nirali Patel, Hui Ye, Pei Luo, Valeria Torres Irizarry, Jacob Vidrine, Ann Coulter, Candida J. Rebello, Sangho Yu, Jia Fan, Hans-Rudolf Berthoud, Frank Greenway, Heike Münzberg, Christopher Morrison, Pingwen Xu, Yanlin He
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Molecular Metabolism
Subjects:
Cav3.2
GABA neurons
Feeding
Hypothalamus
Obesity
Naringenin
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877821002465

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http://www.sciencedirect.com/science/article/pii/S2212877821002465

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