Orthosteric and allosteric modulation of human kinases: A mechanistic view
Human kinases represent a large family of enzymes with their primary function being the phosphorylation of various biomolecules. Kinases along with G-Protein Coupled Receptors (GPCRs) represent two of the most common protein targets in drug discovery. Kinases are classified by the substrate they pho...
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Format: | Article |
Language: | English |
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IMR Press
2020-03-01
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Series: | Frontiers in Bioscience-Landmark |
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Online Access: | https://www.imrpress.com/journal/FBL/25/8/10.2741/4864 |