Orthosteric and allosteric modulation of human kinases: A mechanistic view

Human kinases represent a large family of enzymes with their primary function being the phosphorylation of various biomolecules. Kinases along with G-Protein Coupled Receptors (GPCRs) represent two of the most common protein targets in drug discovery. Kinases are classified by the substrate they pho...

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Bibliographic Details
Main Author: Siddharth Yadav
Format: Article
Language:English
Published: IMR Press 2020-03-01
Series:Frontiers in Bioscience-Landmark
Subjects:
Online Access:https://www.imrpress.com/journal/FBL/25/8/10.2741/4864