Evaluation of Pharmacokinetic Parameters, Toxicity, and Molecular Docking of Flavonols with Aldose Reductase Enzyme to Find an Effective Compound in Inhibition of this Enzyme

Background & Objective: Aldose reductase plays an important role in chronic diabetes and can cause tissue complications. Controlling the activity of aldose reductase provides an important strategy in controlling the complications of diabetes. Flavonoids are important inhibitors of aldose reducta...

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Bibliographic Details
Main Authors: Morteza Sadeghi, Mehran Miroliaei
Format: Article
Language:English
Published: Fasa University of Medical Sciences 2020-11-01
Series:Journal of Advanced Biomedical Sciences
Subjects:
Online Access:http://jabs.fums.ac.ir/article-1-2504-en.pdf