Pharmacokinetic Profile of Fentanyl in the Koala (<i>Phascolarctos cinereus</i>) after Intravenous Administration, and Absorption via a Transdermal Patch

Fentanyl was administered as a single intravenous bolus injection at 5 µg/kg to five koalas and fentanyl plasma concentrations for a minimum of 2 h were quantified by an enzyme-linked immunosorbent assay (ELISA). The median (range) fentanyl elimination half-life and clearance were 0.53 (0.38–0.91) h...

Full description

Bibliographic Details
Main Authors: Fumie Tokonami, Benjamin Kimble, Merran Govendir
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Animals
Subjects:
Online Access:https://www.mdpi.com/2076-2615/11/12/3550