The Crystal Structure Elucidation of a Tetrapeptide Analog of Somatostatin DOTA-Phe-D-Trp-Lys-Thr-OMe

The Crystal Structure Elucidation of a Tetrapeptide Analog of Somatostatin DOTA-Phe-D-Trp-Lys-Thr-OMe

Herewith, we report for the first time the crystal structure of tetrapeptide FwKT (Phe-D-Trp-Lys-Thr), which is considered to represent an epitope for biomedically relevant hormone somatostatin. The target molecule was successfully crystalized, solved and refined as a conjugate of the tetrapeptide m...

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Bibliographic Details
Main Authors: Sabina Diusenova, Sergey Arkhipov, Dmitry Avdeev, Pavel Dorovatovskii, Derenik Khachatryan, Vladimir Lazarenko, Michael Medvedev, Alena Nikolaeva, Mikhail Ovchinnikov, Maria Sidorova, Yan Zubavichus
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Crystals
Subjects:
XRD
analogue
somatostatin
DOTA
PRRT
Online Access:https://www.mdpi.com/2073-4352/12/1/12

Internet

https://www.mdpi.com/2073-4352/12/1/12

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