The moderation effect of GSTM1/GSTT1 gene polymorphisms on the association of sperm mitochondrial DNA copy number and sperm mobility

The moderation effect of GSTM1/GSTT1 gene polymorphisms on the association of sperm mitochondrial DNA copy number and sperm mobility

Abstract Oxidative stress (OS) is believed to be a significant factor in the decline of semen quality, with mitochondrial DNA copy number (mtDNAcn) serving as a sensitive biomarker for both semen quality and mitochondrial dysfunction resulting from oxidative stress. While glutathione S-transferases...

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Bibliographic Details
Main Authors: Tingting Zhang, Shengnan Zhang, Chen Zhang, Huan Liu, Mingming Liu, Guang-hui Zhang, Guangcai Duan, Shuaiyin Chen, Jingchao Ren
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:Scientific Reports
Subjects:
Semen quality
Sperm mitochondrial DNA copy number
GSTM1
GSTT1
Moderation
Interaction
Online Access:https://doi.org/10.1038/s41598-024-74968-3

Internet

https://doi.org/10.1038/s41598-024-74968-3

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