CD22 blockade modulates microglia activity to suppress neuroinflammation following intracerebral hemorrhage

CD22 blockade modulates microglia activity to suppress neuroinflammation following intracerebral hemorrhage

Microglia are first responders to acute brain insults and initiate neuroinflammation to drive secondary tissue injury. Yet the key molecular switches in control of the inflammatory activity of microglia remain poorly understood. Intracerebral hemorrhage (ICH) is a devastating stroke subtype whereby...

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Bibliographic Details
Main Authors: Honglei Ren, Yan Pan, Danni Wang, Hongying Hao, Ranran Han, Caiyun Qi, Wenjun Zhang, Wenyan He, Fu-Dong Shi, Qiang Liu
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Pharmacological Research
Subjects:
Intracerebral hemorrhage
Neuroinflammation
Phagocytosis
Microglia
Spleen tyrosine kinase
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661823002682

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http://www.sciencedirect.com/science/article/pii/S1043661823002682

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