SOCS2 inhibits hepatoblastoma metastasis via downregulation of the JAK2/STAT5 signal pathway

Abstract Metastasis of hepatoblastoma (HB) is a key factor that impairs the prognosis and treatment of children. The suppressor of cytokine signaling 2 (SOCS2) is a classical negative feedback protein that regulates cytokine signal transduction and has been known to be downregulated in several tumor...

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Bibliographic Details
Main Authors: Yong Lv, Xiaolong Xie, Guoyou Zou, Meng Kong, Jiayin Yang, Jing Chen, Bo Xiang
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-48591-7