Accuracy of analysis of cfDNA for detection of single nucleotide variants and copy number variants in breast cancer

Accuracy of analysis of cfDNA for detection of single nucleotide variants and copy number variants in breast cancer

Abstract Background Gene variants are dependable and sensitive biomarkers for target-specific therapies in breast cancer (BC). However, detection of mutations within tissues has many limitations. Plasma circulating free DNA (cfDNA) has been reported in many studies as an alternative tool for detecti...

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Bibliographic Details
Main Authors: Xin Yang, Kuo Zhang, Caiji Zhang, Rongxue Peng, Chengming Sun
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Cancer
Subjects:
PIK3CA
TP53
ESR1
cfDNA
Mutation
Breast cancer
Online Access:http://link.springer.com/article/10.1186/s12885-019-5698-x

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http://link.springer.com/article/10.1186/s12885-019-5698-x

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