Chronometric Administration of Cyclophosphamide and a Double-Stranded DNA-Mix at Interstrand Crosslinks Repair Timing, Called “Karanahan” Therapy, Is Highly Efficient in a Weakly Immunogenic Lewis Carcinoma Model

Chronometric Administration of Cyclophosphamide and a Double-Stranded DNA-Mix at Interstrand Crosslinks Repair Timing, Called “Karanahan” Therapy, Is Highly Efficient in a Weakly Immunogenic Lewis Carcinoma Model

Background and Aims: A new technology based on the chronometric administration of cyclophosphamide and complex composite double-stranded DNA-based compound, which is scheduled in strict dependence on interstrand crosslinks repair timing, and named “Karanahan”, has been developed. Being applied, this...

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Bibliographic Details
Main Authors: Vera Ruzanova, Anastasia Proskurina, Yaroslav Efremov, Svetlana Kirikovich, Genrikh Ritter, Evgenii Levites, Evgenia Dolgova, Ekaterina Potter, Oksana Babaeva, Sergey Sidorov, Oleg Taranov, Alexandr Ostanin, Elena Chernykh, Sergey Bogachev
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Pathology and Oncology Research
Subjects:
cancer stem cells
Karanahan approach
Lewis lung carcinoma
committed tumor cells
tumor growth site
cytostatic agent
Online Access:https://www.por-journal.com/articles/10.3389/pore.2022.1610180/full

Internet

https://www.por-journal.com/articles/10.3389/pore.2022.1610180/full

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