Remodeling the conformational dynamics of I-motif DNA by helicases in ATP-independent mode at acidic environment

Summary: I-motifs are noncanonical four-stranded DNA structures formed by C-rich sequences at acidic environment with critical biofunctions. The particular pH sensitivity has inspired the development of i-motifs as pH sensors and DNA motors in nanotechnology. However, the folding and regulation mech...

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Bibliographic Details
Main Authors: Bo Gao, Ya-Ting Zheng, Ai-Min Su, Bo Sun, Xu-Guang Xi, Xi-Miao Hou
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221015455