Targeted therapy for tuberous sclerosis complex

The tuberous sclerosis complex genes (TSC1 and TSC2) function as classic tumor suppressor genes in health; a loss of function of these genes results in activation of the kinase m-TOR and to development of benign tumors. Despite their slow progression, renal subependymal giant cell astrocytomas and a...

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Bibliographic Details
Main Authors: E. D. Belousova, D. V. Vlodavets, A. M. Pivovarova, O. V. Katysheva, M. Yu. Dorofeeva
Format: Article
Language:Russian
Published: Ltd. “The National Academy of Pediatric Science and Innovation” 2016-11-01
Series:Rossijskij Vestnik Perinatologii i Pediatrii
Subjects:
Online Access:https://www.ped-perinatology.ru/jour/article/view/390