Targeted therapy for tuberous sclerosis complex
The tuberous sclerosis complex genes (TSC1 and TSC2) function as classic tumor suppressor genes in health; a loss of function of these genes results in activation of the kinase m-TOR and to development of benign tumors. Despite their slow progression, renal subependymal giant cell astrocytomas and a...
Main Authors: | , , , , |
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Format: | Article |
Language: | Russian |
Published: |
Ltd. “The National Academy of Pediatric Science and Innovation”
2016-11-01
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Series: | Rossijskij Vestnik Perinatologii i Pediatrii |
Subjects: | |
Online Access: | https://www.ped-perinatology.ru/jour/article/view/390 |