Scc2 counteracts a Wapl-independent mechanism that releases cohesin from chromosomes during G1
Cohesin’s association with chromosomes is determined by loading dependent on the Scc2/4 complex and release due to Wapl. We show here that Scc2 also actively maintains cohesin on chromosomes during G1 in S. cerevisiae cells. It does so by blocking a Wapl-independent release reaction that requires op...
Main Authors: | , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2019-06-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/44736 |