Non-Omicron breakthrough infection with higher viral load and longer vaccination-infection interval improves SARS-CoV-2 BA.4/5 neutralization

Non-Omicron breakthrough infection with higher viral load and longer vaccination-infection interval improves SARS-CoV-2 BA.4/5 neutralization

Summary: The immune responses to SARS-CoV-2 variants in COVID-19 cases are influenced by various factors including pre-existing immunity via vaccination and prior infection. Elucidating the drivers for upgrading neutralizing activity to SARS-CoV-2 in COVID-19 cases with pre-existing immunity will ai...

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Bibliographic Details
Main Authors: Sho Miyamoto, Takeshi Arashiro, Akira Ueno, Takayuki Kanno, Shinji Saito, Harutaka Katano, Shun Iida, Akira Ainai, Seiya Ozono, Takuya Hemmi, Yuichiro Hirata, Saya Moriyama, Ryutaro Kotaki, Hitomi Kinoshita, Souichi Yamada, Masaharu Shinkai, Shuetsu Fukushi, Yoshimasa Takahashi, Tadaki Suzuki
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:iScience
Subjects:
Immunology
Immune response
Virology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223000469

Internet

http://www.sciencedirect.com/science/article/pii/S2589004223000469

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