Knockout of mlaA increases Escherichia coli virulence in a silkworm infection model.

The mlaA gene encodes a lipoprotein to maintain an outer membrane lipid asymmetry in gram-negative bacteria. Although the role of mlaA in bacterial virulence has been studied in several bacterial species, there are no reports of its role in E. coli virulence. In this study, we found that knockout of...

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Bibliographic Details
Main Authors: Haruka Nasu, Riko Shirakawa, Kazuyuki Furuta, Chikara Kaito
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0270166