Interleukin-33 Induces Neutrophil Extracellular Trap (NET) Formation and Macrophage Necroptosis via Enhancing Oxidative Stress and Secretion of Proatherogenic Factors in Advanced Atherosclerosis

Interleukin-33 Induces Neutrophil Extracellular Trap (NET) Formation and Macrophage Necroptosis via Enhancing Oxidative Stress and Secretion of Proatherogenic Factors in Advanced Atherosclerosis

Interleukin-33 (IL-33) acts as an ‘alarmin’, and its role has been demonstrated in driving immune regulation and inflammation in many human diseases. However, the precise mechanism of action of IL-33 in regulating neutrophil and macrophage functioning is not defined in advanced atherosclerosis (aAT)...

ver descrição completa

Detalhes bibliográficos
Principais autores: Manoj Kumar Tembhre, Mukesh Kumar Sriwastva, Milind Padmakar Hote, Shikha Srivastava, Priyanka Solanki, Shafaque Imran, Ramakrishnan Lakshmy, Alpana Sharma, Kailash Jaiswal, Ashish Datt Upadhyay
Formato: Artigo
Idioma:English
Publicado em: MDPI AG 2022-11-01
coleção:Antioxidants
Assuntos:
Interleukin-33
NETs
necroptosis
advanced atherosclerosis
myeloperoxidases (MPO)
macrophages
Acesso em linha:https://www.mdpi.com/2076-3921/11/12/2343

Internet

https://www.mdpi.com/2076-3921/11/12/2343

Registros relacionados