Deciphering the Role of the Anaphylatoxin C3a: A Key Function in Modulating the Tumor Microenvironment

Deciphering the Role of the Anaphylatoxin C3a: A Key Function in Modulating the Tumor Microenvironment

The complement system plays a crucial role in cancer development. Our study investigated the role of C3a anaphylatoxin on the tumor microenvironment. Our models consisted of mesenchymal stem cells (MSC-like, 3T3-L1), macrophages (Raw 264.7 Blue, (RB)) and tumor cells (melanoma B16/F0). Recombinant m...

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Bibliographic Details
Main Authors: Jolimar Hanna, Franck Ah-Pine, Chailas Boina, Yosra Bedoui, Philippe Gasque, Axelle Septembre-Malaterre
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Cancers
Subjects:
tumor
anaphylatoxin C3a
complement
tumor microenvironment
Online Access:https://www.mdpi.com/2072-6694/15/11/2986

Internet

https://www.mdpi.com/2072-6694/15/11/2986

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