Prediction of lncRNA-disease association based on a Laplace normalized random walk with restart algorithm on heterogeneous networks

Prediction of lncRNA-disease association based on a Laplace normalized random walk with restart algorithm on heterogeneous networks

Abstract Background More and more evidence showed that long non-coding RNAs (lncRNAs) play important roles in the development and progression of human sophisticated diseases. Therefore, predicting human lncRNA-disease associations is a challenging and urgently task in bioinformatics to research of h...

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Bibliographic Details
Main Authors: Liugen Wang, Min Shang, Qi Dai, Ping-an He
Format: Article
Language:English
Published: BMC 2022-01-01
Series:BMC Bioinformatics
Subjects:
lncRNA-disease associations
Similarity network
Heterogeneous network
LRWRHLDA
Ten-fold cross validation
AUC
Online Access:https://doi.org/10.1186/s12859-021-04538-1

Internet

https://doi.org/10.1186/s12859-021-04538-1

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