Transcriptomic profile comparison of monocytes from rheumatoid arthritis patients in treatment with methotrexate, anti-TNFa, abatacept or tocilizumab.

It is well documented that patients affected by rheumatoid arthritis (RA) have distinct susceptibility to the different biologic DMARDs available on the market, probably because of the many facets of the disease. Monocytes are deeply involved in the pathogenesis of RA and we therefore evaluated and...

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Main Authors: Maria Talmon, Marcella Percio, Joyce Afrakoma Obeng, Federico A Ruffinatti, Daniele Sola, Pier Paolo Sainaghi, Emanuela Bellis, Stefano Cusinato, Aurora Ianniello, Luigia G Fresu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0282564