Sparse genetic tracing reveals regionally specific functional organization of mammalian nociceptors

Sparse genetic tracing reveals regionally specific functional organization of mammalian nociceptors

The human distal limbs have a high spatial acuity for noxious stimuli but a low density of pain-sensing neurites. To elucidate mechanisms underlying regional differences in processing nociception, we sparsely traced non-peptidergic nociceptors across the body using a newly generated MrgprdCreERT2 mo...

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Bibliographic Details
Main Authors: William Olson, Ishmail Abdus-Saboor, Lian Cui, Justin Burdge, Tobias Raabe, Minghong Ma, Wenqin Luo
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-10-01
Series:eLife
Subjects:
nociceptor
pain fovea
somatotopic organization
single neuron morphology
Online Access:https://elifesciences.org/articles/29507

Internet

https://elifesciences.org/articles/29507

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