MicroRNA-22 Induces Endothelial Progenitor Cell Senescence by Targeting AKT3

MicroRNA-22 Induces Endothelial Progenitor Cell Senescence by Targeting AKT3

Objectives: Endothelial progenitor cells (EPCs) play an important role in postnatal neovascularization. The number and function of EPCs declines as part of aging-associated senescence, thereby potentially contributing to vascular pathologies. Here, we investigated the significance and molecular mech...

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Bibliographic Details
Main Authors: Yue Zheng, Zhiwei Xu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-10-01
Series:Cellular Physiology and Biochemistry
Subjects:
Aging
Senescence
Angiogenesis
AKT3
Endothelial progenitor cells
Online Access:http://www.karger.com/Article/FullText/366358

Internet

http://www.karger.com/Article/FullText/366358

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