The Effect of Biological Sex on Arterial Stiffness and Renin-Angiotensin-Aldosterone System Activity in Response to Cyclooxygenase-2 (COX-2) Inhibition

The Effect of Biological Sex on Arterial Stiffness and Renin-Angiotensin-Aldosterone System Activity in Response to Cyclooxygenase-2 (COX-2) Inhibition

Background: Cardiovascular disease is the leading cause of death globally. Cyclooxygenase (COX)-derived prostaglandins play an important role in cardiovascular health regulation. Animal studies suggest a greater vascular dependence on prostaglandins in female subjects, but whether this extends to hu...

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Bibliographic Details
Main Authors: Chantal L. Rytz, MSc, Sandra M. Dumanski, MD, MSc, FRCPC, Darlene Y. Sola, BScN, RN, Sofia B. Ahmed, MD, MMSc, FRCPC
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:CJC Open
Online Access:http://www.sciencedirect.com/science/article/pii/S2589790X22002487

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http://www.sciencedirect.com/science/article/pii/S2589790X22002487

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