New Imatinib Derivatives with Antiproliferative Activity against A549 and K562 Cancer Cells

Tyrosine kinase enzymes are among the primary molecular targets for the treatment of some human neoplasms, such as those in lung cancer and chronic myeloid leukemia. Mutations in the enzyme domain can cause resistance and new inhibitors capable of circumventing these mutations are highly desired. Th...

Full description

Bibliographic Details
Main Authors: Andressa Oliveira, Stefany Moura, Luiz Pimentel, João Neto, Rafael Dantas, Floriano Silva-Jr, Monica Bastos, Nubia Boechat
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/27/3/750