Targeting the lipid metabolic axis ACSL/SCD in colorectal cancer progression by therapeutic miRNAs: miR-19b-1 role[S]

Targeting the lipid metabolic axis ACSL/SCD in colorectal cancer progression by therapeutic miRNAs: miR-19b-1 role[S]

An abnormal acyl-CoA synthetase/stearoyl-CoA desaturase (ACSL/SCD) lipid network fuels colon cancer progression, endowing cells with invasive and migratory properties. Therapies against this metabolic network may be useful to improve clinical outcomes. Because micro-RNAs (miRNAs/miRs) are important...

Full description

Bibliographic Details
Main Authors: Silvia Cruz-Gil, Ruth Sanchez-Martinez, Marta Gomez de Cedron, Roberto Martin-Hernandez, Teodoro Vargas, Susana Molina, Jesús Herranz, Alberto Davalos, Guillermo Reglero, Ana Ramirez de Molina
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Journal of Lipid Research
Subjects:
micro-ribonucleic acid
colorectal tumors
patient relapse
invasiveness
molecular biology
lipid and lipoprotein metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520339286

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520339286

Similar Items