Single-cell transcriptomics of hepatic stellate cells uncover crucial pathways and key regulators involved in non-alcoholic steatohepatitis

Background: Fibrosis is an important pathological process in the development of non-alcoholic steatohepatitis (NASH), and the activation of hepatic stellate cell (HSC) is a central event in liver fibrosis. However, the transcriptomic change of activated HSCs (aHSCs) and resting HSCs (rHSCs) in NASH...

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Bibliographic Details
Main Authors: Weiwei He, Caoxin Huang, Xiulin Shi, Menghua Wu, Han Li, Qiuhong Liu, Xiaofang Zhang, Yan Zhao, Xuejun Li
Format: Article
Language:English
Published: Bioscientifica 2023-01-01
Series:Endocrine Connections
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Online Access:https://ec.bioscientifica.com/view/journals/ec/12/2/EC-22-0502.xml