A randomized placebo−controlled clinical trial of oral green tea epigallocatechin 3−gallate on erythropoiesis and oxidative stress in transfusion−dependent β−thalassemia patients

A randomized placebo−controlled clinical trial of oral green tea epigallocatechin 3−gallate on erythropoiesis and oxidative stress in transfusion−dependent β−thalassemia patients

β−Thalassemia patients suffer from ineffective erythropoiesis and increased red blood cell (RBC) hemolysis. Blood transfusion, erythropoietic enhancement, and antioxidant supplementation can ameliorate chronic anemia. Green tea extract (GTE) is comprised of catechin derivatives, of which epigallocat...

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Bibliographic Details
Main Authors: Kornvipa Settakorn, Sasinee Hantrakool, Touchwin Petiwathayakorn, Nuntouchaporn Hutachok, Adisak Tantiworawit, Pimlak Charoenkwan, Nopphadol Chalortham, Anchan Chompupoung, Narisara Paradee, Pimpisid Koonyosying, Somdet Srichairatanakool
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Molecular Biosciences
Subjects:
green tea
epigallocatechin-3-gallate
thalassemia
iron overload
erythropoiesis
erythroferrone
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1248742/full

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https://www.frontiersin.org/articles/10.3389/fmolb.2023.1248742/full

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