The Effect of Residual Triton X-100 on Structural Stability and Infection Activity of Adenovirus Particles

The Effect of Residual Triton X-100 on Structural Stability and Infection Activity of Adenovirus Particles

To ensure the high purity and biological activity of the adenovirus vector to be used for clinical applications, a stable and linearly scalable preparation method is highly imperative. During the adenovirus-harvesting process, the Triton X-100-based lysis method possesses the advantages of higher ef...

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Bibliographic Details
Main Authors: Jinhu Ma, Chao Su, Shichuan Hu, Yanwei Chen, Yongheng Shu, Dan Yue, Bin Zhang, Zhongbing Qi, Suli Li, Xilei Wang, Yueting Kuang, Ping Cheng
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Molecular Therapy: Methods & Clinical Development
Subjects:
adenovirus
Triton X-100
purification
stability
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050120301790

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http://www.sciencedirect.com/science/article/pii/S2329050120301790

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