Rho GTPases in Retinal Vascular Diseases

Rho GTPases in Retinal Vascular Diseases

The Rho family of small GTPases (Rho GTPases) act as molecular switches that transduce extrinsic stimuli into cytoskeletal rearrangements. In vascular endothelial cells (ECs), Cdc42, Rac1, and RhoA control cell migration and cell–cell junctions downstream of angiogenic and inflammatory cytokines, th...

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Bibliographic Details
Main Authors: Akiyoshi Uemura, Yoko Fukushima
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
angiogenesis
cell–cell junction
cell migration
endothelial cell
retina
Rho GTPase
Online Access:https://www.mdpi.com/1422-0067/22/7/3684

Internet

https://www.mdpi.com/1422-0067/22/7/3684

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