Rho GTPases in Retinal Vascular Diseases
The Rho family of small GTPases (Rho GTPases) act as molecular switches that transduce extrinsic stimuli into cytoskeletal rearrangements. In vascular endothelial cells (ECs), Cdc42, Rac1, and RhoA control cell migration and cell–cell junctions downstream of angiogenic and inflammatory cytokines, th...
Main Authors: | Akiyoshi Uemura, Yoko Fukushima |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-04-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/22/7/3684 |
Similar Items
-
The Role of Fast-Cycling Atypical RHO GTPases in Cancer
by: Pontus Aspenström
Published: (2022-04-01) -
RhoGTPase in Vascular Disease
by: Derek Strassheim, et al.
Published: (2019-06-01) -
Building Blood Vessels—One Rho GTPase at a Time
by: Haley Rose Barlow, et al.
Published: (2019-06-01) -
Extraction of active RhoGTPases by RhoGDI regulates spatiotemporal patterning of RhoGTPases
by: Adriana E Golding, et al.
Published: (2019-10-01) -
Skin Cancers and the Contribution of Rho GTPase Signaling Networks to Their Progression
by: Alessandra Pecora, et al.
Published: (2021-08-01)