UPF1 contributes to the maintenance of endometrial cancer stem cell phenotype by stabilizing LINC00963

Abstract Endometrial cancer stem cells (ECSCs) play a vital role in endometrial cancer (EC) metastasis, relapse, and chemoresistance. However, the molecular mechanisms that sustain ECSCs remain elusive. Here, we showed that the expression of UPF1 was upregulated in EC tissues and ECSCs and correlate...

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Bibliographic Details
Main Authors: Hao Chen, Jian Ma, Fanfei Kong, Ning Song, Cuicui Wang, Xiaoxin Ma
Format: Article
Language:English
Published: Nature Publishing Group 2022-03-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-04707-x