Baf45a Mediated Chromatin Remodeling Promotes Transcriptional Activation for Osteogenesis and Odontogenesis

Baf45a Mediated Chromatin Remodeling Promotes Transcriptional Activation for Osteogenesis and Odontogenesis

Chromatin remodeling, specifically the tissue-specific regulation in mineralized tissues, is an understudied avenue of gene regulation. Here we show that Baf45a and Baf45d, two Baf45 homologs belong to ATPase-dependent SWI/SNF chromatin remodeling complex, preferentially expressed in osteoblasts and...

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Bibliographic Details
Main Authors: Theodore Busby, Yuechuan Chen, Tanner C. Godfrey, Mohammad Rehan, Benjamin J. Wildman, Caris M. Smith, Quamarul Hassan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Endocrinology
Subjects:
Baf45a
Brg1/Smarca4
osteoblastogenesis
chromatin remodeling
PBAF complex
dentinogenesis
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.763392/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2021.763392/full

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