Qualifying Osteogenic Potency Assay Metrics for Human Multipotent Stromal Cells: TGF-β2 a Telling Eligible Biomarker

Qualifying Osteogenic Potency Assay Metrics for Human Multipotent Stromal Cells: TGF-β2 a Telling Eligible Biomarker

Potency assays are critical for regenerative medicine, addressing the known challenge of functional heterogeneity among human multipotent stromal cells (hMSC). Necessary laboratory cell expansion allows analysis before implantation in the patient. Levels of induction of five signature gene biomarker...

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Bibliographic Details
Main Authors: Augustin M. Ofiteru, Diana F. Becheru, Sami Gharbia, Cornel Balta, Hildegard Herman, Bianca Mladin, Mariana Ionita, Anca Hermenean, Jorge S. Burns
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Cells
Subjects:
bone
multipotent stromal cells
stem cells
adipose tissue
bone marrow
gene expression
Online Access:https://www.mdpi.com/2073-4409/9/12/2559

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https://www.mdpi.com/2073-4409/9/12/2559

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