Efficient expression of heterologous genes by the introduction of the endogenous glyceraldehyde-3-phosphate dehydrogenase gene intron 1 in Ganoderma lucidum

Efficient expression of heterologous genes by the introduction of the endogenous glyceraldehyde-3-phosphate dehydrogenase gene intron 1 in Ganoderma lucidum

Abstract Background Ganoderma lucidum, a well-known medicinal mushroom, has received wide attention as a promising cell factory for producing bioactive compounds. However, efficient expression of heterologous genes remains a major challenge in Ganoderma, hindering metabolic regulation research and m...

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Bibliographic Details
Main Authors: Hao You, Bin Sun, Na Li, Jun-Wei Xu
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Microbial Cell Factories
Subjects:
Ganoderma
Expression of heterologous genes
Intron
mRNA accumulation
Protein expression
Enzyme activity
Online Access:https://doi.org/10.1186/s12934-021-01654-8

Internet

https://doi.org/10.1186/s12934-021-01654-8

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