Local energetic frustration conservation in protein families and superfamilies

Local energetic frustration conservation in protein families and superfamilies

Abstract Energetic local frustration offers a biophysical perspective to interpret the effects of sequence variability on protein families. Here we present a methodology to analyze local frustration patterns within protein families and superfamilies that allows us to uncover constraints related to s...

Full description

Bibliographic Details
Main Authors: Maria I. Freiberger, Victoria Ruiz-Serra, Camila Pontes, Miguel Romero-Durana, Pablo Galaz-Davison, Cesar A. Ramírez-Sarmiento, Claudio D. Schuster, Marcelo A. Marti, Peter G. Wolynes, Diego U. Ferreiro, R. Gonzalo Parra, Alfonso Valencia
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-43801-2

Internet

https://doi.org/10.1038/s41467-023-43801-2

Similar Items