Antimicrobial Human β-Defensins in the Colon and Their Role in Infectious and Non-Infectious Diseases

β-defensins are small cationic antimicrobial peptides secreted by diverse cell types including colonic epithelial cells. Human β-defensins form an essential component of the intestinal lumen in innate immunity. The defensive mechanisms of β-defensins include binding to negatively charged microbial m...

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Bibliographic Details
Main Authors: Eduardo R. Cobo, Kris Chadee
Format: Article
Language:English
Published: MDPI AG 2013-03-01
Series:Pathogens
Subjects:
Online Access:http://www.mdpi.com/2076-0817/2/1/177