Assessment of the DNA Mismatch Repair System Is Crucial in Colorectal Cancers Necessitating Adjuvant Treatment: A Propensity Score-Matched and Win Ratio Analysis

Assessment of the DNA Mismatch Repair System Is Crucial in Colorectal Cancers Necessitating Adjuvant Treatment: A Propensity Score-Matched and Win Ratio Analysis

A deficient DNA mismatch repair (MMR) system is identified in a non-negligible part of sporadic colorectal cancers (CRCs), and its prognostic value remains controversial. High tumor mutational burden, along with a poor response to conventional chemotherapy and excellent results from immunotherapy, a...

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Bibliographic Details
Main Authors: Eva Lieto, Francesca Cardella, Duolao Wang, Andrea Ronchi, Giovanni Del Sorbo, Iacopo Panarese, Francesca Ferraraccio, Ferdinando De Vita, Gennaro Galizia, Annamaria Auricchio
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Cancers
Subjects:
colorectal cancers
DNA mismatch repair system
immunotherapy
win ratio
Online Access:https://www.mdpi.com/2072-6694/16/1/134

Internet

https://www.mdpi.com/2072-6694/16/1/134

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