CatSperζ regulates the structural continuity of sperm Ca2+ signaling domains and is required for normal fertility
We report that the Gm7068 (CatSpere) and Tex40 (CatSperz) genes encode novel subunits of a 9-subunit CatSper ion channel complex. Targeted disruption of CatSperz reduces CatSper current and sperm rheotactic efficiency in mice, resulting in severe male subfertility. Normally distributed in linear qua...
| Main Authors: | , , , , , , , , , |
|---|---|
| 格式: | 文件 |
| 语言: | English |
| 出版: |
eLife Sciences Publications Ltd
2017-02-01
|
| 丛编: | eLife |
| 主题: | |
| 在线阅读: | https://elifesciences.org/articles/23082 |