Image improvement of temporal focusing multiphoton microscopy via superior spatial modulation excitation and Hilbert–Huang transform decomposition

Abstract Temporal focusing-based multiphoton excitation microscopy (TFMPEM) just provides the advantage of widefield optical sectioning ability with axial resolution of several micrometers. However, under the plane excitation, the photons emitted from the molecules in turbid tissues undergo scatteri...

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Bibliographic Details
Main Authors: Yvonne Yuling Hu, Chun-Yu Lin, Chia-Yuan Chang, Yuan-Long Lo, Shean-Jen Chen
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-14367-8