The Protective Effects of Parathyroid Hormone (1‐34) on Cartilage and Subchondral Bone Through Down‐Regulating JAK2/STAT3 and WNT5A/ROR2 in a Collagenase‐Induced Osteoarthritis Mouse Model
Objective To assess the effects of PTH (1‐34) on bone and cartilage metabolism in a collagenase‐induced mouse model of osteoarthritis (OA) and examine whether PTH (1‐34) affects the expression of JAK2/STAT3 and WNT5A/ROR2 in this process. Methods Eighteen 12‐week‐old male C57Bl/6 mice were randomly...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2021-07-01
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| Series: | Orthopaedic Surgery |
| Subjects: | |
| Online Access: | https://doi.org/10.1111/os.13019 |