Interaction between Hemin and Prion Peptides: Binding, Oxidative Reactivity and Aggregation

Interaction between Hemin and Prion Peptides: Binding, Oxidative Reactivity and Aggregation

We investigate the interaction of hemin with four fragments of prion protein (PrP) containing from one to four histidines (PrP<sub>106–114</sub>, PrP<sub>95–114</sub>, PrP<sub>84–114</sub>, PrP<sub>76–114</sub>) for its potential relevance to prion dis...

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Bibliographic Details
Main Authors: Simone Dell’Acqua, Elisa Massardi, Enrico Monzani, Giuseppe Di Natale, Enrico Rizzarelli, Luigi Casella
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
hemin
prion peptides
prion diseases
oxidative stress
neurodegeneration
peroxidase
Online Access:https://www.mdpi.com/1422-0067/21/20/7553

Internet

https://www.mdpi.com/1422-0067/21/20/7553

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