A Mouse-Specific Model to Detect Genes under Selection in Tumors

The mouse is a widely used model organism in cancer research. However, no computational methods exist to identify cancer driver genes in mice due to a lack of labeled training data. To address this knowledge gap, we adapted the GUST (Genes Under Selection in Tumors) model, originally trained on huma...

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Bibliographic Details
Main Authors: Hai Chen, Jingmin Shu, Carlo C. Maley, Li Liu
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/15/21/5156